CHOLINESTERASE, 5 x 30 mL

PRINCIPLE

Cholinesterase hydrolyzes butyrylthiocholine to thiocholine, that reacts with DTNB *producing a yellow compound measured at 405 nm. At optimum reaction conditions, the ?Abs is directly related to cholinesterase activity of the sample.

* DTNB: dithiobis-nitrobenzoate.

DIAGNOSTIC USE

Cholinesterase values are decreased in liver disease, in processes that occur with hypoalbuminemia and in poisoning by organophosphates.

Increases in activity occur in patients suffering from hipelipoproteinemia type IV, in myasthenia gravis and nephrosis.

Single test result can not be used to make a clinical diagnosis. It should integrate clinical and laboratory data.